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Medchemexpress LLC Mc-Val-Cit-PAB-Cl | 1639351-92-0 | 95.0% | 591.10 | 10 MG

Supplier: Medchemexpress LLC HY11209910MG
Mc-Val-Cit-PAB-Cl is a cleavable Antibody-Drug Conjugate (ADC) linker. It can be used to conjugate MMAE and an antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). ADCs are composed of an antibody to which an ADC cytotoxin is attached via an ADC linker. It is for research use only.
- Cleavable ADC linker
- Can be used to conjugate MMAE and antibody
- Applicable in forming antibody-MC-vc-MMAE
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