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Medchemexpress LLC MC4033 KAT8 inhibitor | 28532-21-0 | 98.3% | 295.29 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1493021MG

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MC4033 is a compound that shows inhibitory activity against KAT8 (lysine acetyltransferase 8) with an IC50 of 12.1 μM. It has demonstrated antiproliferative effects in various human cancer cell lines, including HCT116, H1299, A549, and U937, with IC50 values ranging from 30.1 μM to 52.1 μM. Additionally, MC4033 has been shown to reduce the level of H4K16Ac in HT29 cells, suggesting its ability to inhibit KAT8 in cells.

  • KAT8 inhibitor.
  • Antiproliferative effects in several cancer cell lines.
  • Induces apoptosis.
  • Reduces oncogene mRNA levels.
  • Activates autophagy.
  • Synergistic apoptotic effect.

Catalog No. 50-003-59577


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