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Medchemexpress LLC HY-114312 5mg Medchemexpress, MD-224 CAS:2136247-12-4 Purity:>98%
Supplier: Medchemexpress LLC HY1143125MG
Medchemexpress, HY-114312 5mg MD-224 CAS:2136247-12-4 MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 induces rapid degradation of MDM2 at concentrations <1 nM in human leukemia cells, and achieves an IC50 value of 1.5 nM in inhibition of growth of RS4;11 cells. MD-224 has the potential to be a new class of anticancer agent. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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