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Medchemexpress LLC MDA 19 | 1048973-47-2 | C21H23N3O2 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1545110MM/1ML

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MDA 19 is a potent and selective agonist of human cannabinoid receptor 2 (CB2), with a Ki of 43.3 nM. It exhibits antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity. This compound has been pharmacologically characterized for its activity at cannabinoid receptors.

  • Potent and selective agonist of human cannabinoid receptor 2 (CB2).
  • Exhibits antiallodynic effects in rat models of neuropathic pain.
  • Does not affect rat locomotor activity.
  • Displays higher affinity for human CB2 than human CB1 receptors.
  • Shows significantly higher affinity for rat CB2 than rat CB1 receptors.
  • Acts as an agonist at human CB1 and CB2 receptors, and rat CB1 receptor in functional assays.
  • Behaves as an inverse agonist at the rat CB2 receptor in some functional assays.
  • Attenuates tactile allodynia in rats and CB2(+/+) mice via CB2 receptor mediation.

Catalog No. 50-003-76442


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