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Enzo Life Sciences Mdivi-1, (10mg), CAS Number: 338967-87-6
SDP

Supplier:  Enzo Life Sciences BMLCM1270010

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Inhibitor of mitochondrial division. Mdivi-1 is a selective inhibitor of mitochondrial division in yeast and mammalian cells which acts via inhibiting the mitochondrial division dynamin. In cells, Mdivi-1 inhibits apoptosis by inhibiting mitochondrial outer membrane permeabilization. Mdivi-1 causes the rapid (50= ~10µM. In yeast, time-lapse fluorescence microscopy revealed no detectable mitochondrial division after treatment with Mdivi-1. It inhibits Dnm1 GTPase activity in a dose dependent manner with an estimated IC50 of 1-10µM but is not a general inhibitor of GTPases. Formula: C15H10Cl2N2O2S. MW: 353.2. CAS Number: 338967-87-6. Purity: ≥97% (HPLC). Appearance: White solid. Solubility: Soluble in DMSO (25mg/ml). Long Term Storage: -20°C

Catalog No. NC9015141


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