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Apexbio Technology LLC MDL-29951 130798-51-5 100mg
Supplier: Apexbio Technology LLC B1038100
MDL-29951 (CAS 130798-51-5) is a small molecule inhibitor targeting the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor By antagonizing glycine-induced receptor activation MDL-29951 modulates NMDA receptor-mediated neurotransmission In vitro assays measuring [3H]glycine binding determined a Ki value of 0 14 mM indicating its affinity for the glycine site MDL-29951 is utilized in biomedical research to investigate the functional role of glycine co-agonism in NMDA receptor signaling and to explore the pharmacological modulation of glutamatergic pathways in neurological models
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