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Selleck Chemical LLC ME-344 S9736-5MG
Supplier: Selleck Chemical LLC S97365MG
ME-344 is a synthetic metabolite of NV-128 a potent inhibitor of mitochondrial oxidative phosphorylation (OXPHOS) complex I disrupting ATP generation and oxygen consumption It also inhibits mTOR by downregulating the AKT/mTOR pathway exhibiting anticancer activity by inhibiting cell growth and viability in leukemia cell lines with IC50 values of 70 260 nM
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