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Apexbio Technology LLC Medetomidine HCl 86347-15-1 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B13615.1
Medetomidine HCl (CAS 86347-15-1) is a potent and highly selective agonist of the 2-adrenoceptor with a binding affinity (K sub i /sub ) of 1 08 nM Demonstrating approximately 1620-fold greater selectivity for 2- over 1-adrenoceptors medetomidine modulates adrenergic signaling predominantly via presynaptic inhibition of norepinephrine release This selectivity makes medetomidine a valuable tool for studies involving 2-adrenergic receptor pharmacology including research on neurotransmitter modulation central nervous system function and cardiovascular physiology
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