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Apexbio Technology LLC Mertansine 139504-50-0 100mg
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Supplier:  Apexbio Technology LLC BA2321100

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Mertansine (CAS 139504-50-0) also known as DM1 is a maytansinoid microtubule inhibitor that binds to tubulin and disrupts microtubule assembly leading to cell cycle arrest and apoptosis Due to its high cytotoxicity mertansine is commonly used as the cytotoxic payload in antibody drug conjugates (ADCs) where it is covalently linked to monoclonal antibodies via specific linkers This design facilitates targeted delivery of the compound to tumor cells thereby minimizing systemic toxicity and enhancing tumor specificity Mertansine is widely utilized in preclinical and clinical studies of targeted cancer therapeutics

Catalog No. 50-000-91328


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