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Medchemexpress LLC MET kinase-IN-4 | 888719-03-7 | 99.0% | 458.42 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1830950MG

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MET kinase-IN-4 is an orally active Met kinase inhibitor with potent Met kinase inhibitory activity (IC50 = 1.9 nM). It also inhibits Flt-3 and VEGFR-2 kinases. This compound shows good metabolic stability and can be used for cancer research. It exhibits a favorable pharmacokinetic profile in mice and demonstrates significant antitumor activity in the GTL-16 human gastric carcinoma xenograft model.

  • Orally active Met kinase inhibitor
  • Potent Met kinase inhibitory activity (IC50 = 1.9 nM)
  • Inhibits Flt-3 and VEGFR-2 kinases
  • Good metabolic stability in human and mouse liver microsomes
  • Suitable for cancer research
  • Exhibits favorable pharmacokinetic profile in mice
  • Demonstrates significant antitumor activity in GTL-16 human gastric carcinoma xenograft model

Catalog No. 50-003-87562


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