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Medchemexpress LLC Methanone, (5-methoxy-1H-indol-2-yl)phenyl- | 74588-78-6 | C16H13NO2 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY15482

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D-64131 is an orally active tubulin inhibitor, exhibiting antimitotic activity and primarily used for cancer research. It effectively inhibits tubulin polymerization with an IC50 of 0.53 μM.

  • Binds to β-tubulin, destabilizing microtubules and arresting mitotic cells in M-phase
  • Inhibits proliferation of tumor cells from various organs and tissues
  • Cytotoxic toward MDR/MRP tumor cell lines
  • Suppresses U373 proliferation and cell cycle
  • Significantly inhibits tumor growth in human amelanoic melanoma xenograft models in vivo
  • Exhibits oral bioavailability and is well tolerated at efficacious doses

Catalog No. 50-003-75235


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