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Medchemexpress LLC Methanone, 8-oxa-2-azaspiro [4.5]dec-2-yl[2-[(2-pyrazinylmethyl)amino]-5-pyrimidinyl]- | 2173134-00-2 | 99.9% | 10 MM * 1 ML

Supplier: Medchemexpress LLC HY12903510MM/1ML
PFI-653 is a chemical probe and a potent vanin-1 inhibitor, also known as Vanin-1-IN-1. It targets cell surface-associated inositol (GPi)-anchored protein vanin-1, which is involved in metabolism and inflammation. This compound effectively binds to and inhibits plasma vanin-1 across various species, including human, mouse, rat, and dog.
- Chemical probe and vanin-1 inhibitor
- Binds to plasma vanin-1 from multiple species
- Exhibits low clearance rate and high bioavailability in vivo
- Relevant for research in metabolism and inflammation
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