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Medchemexpress LLC Methylnissolin (astrapterocarpan) | 73340-41-7 | 1 MG
Supplier: Medchemexpress LLC HYN24841MG
Methylnissolin (Astrapterocarpan) is an osteoclast inhibitor exhibiting anti-inflammatory, neuroprotective, and antioxidant activities. It is applicable to research related to ischemic stroke, osteoporosis, cardiovascular diseases, and skin aging.
- Downregulates the activation of MAPK and PI3K/AKT pathways
- Inhibits the phosphorylation of MAPK1 and AKT1
- Blocks PDGF-BB-induced phosphorylation of ERK1/2
- Reduces the expression and secretion of proinflammatory mediators
- Decreases intracellular ROS levels
- Upregulates antioxidant enzymes
- Downregulates osteoclastogenesis markers
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