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Medchemexpress LLC Mezigdomide | 2259648-80-9 | 99.2% | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY129395

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Mezigdomide (CC-92480) is a cereblon E3 ubiquitin ligase modulating agent (CELMoD) that acts as a molecular glue. It exhibits high affinity to cereblon, leading to potent antimyeloma activity. This product is classified with several hazards including acute oral toxicity, skin and eye irritation, respiratory tract irritation, and suspected reproductive toxicity. It is stable under recommended storage conditions.

  • Cereblon E3 ubiquitin ligase modulating agent (CELMoD)
  • Acts as a molecular glue
  • High affinity to cereblon
  • Potent antimyeloma activity
  • Effective in CC-5013, CC-4047, and CC-220-resistant cell lines
  • Induces loss of Aiolos and Ikaros in cultured PBMCs
  • Harmful if swallowed
  • Causes skin and serious eye irritation
  • May cause respiratory irritation
  • Suspected of damaging fertility or the unborn child

Catalog No. 50-003-39701


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