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Medchemexpress LLC MGD-28 | 2991818-13-2 | 99.7% | 595.67 | 100 MG

Supplier: Medchemexpress LLC HY168615100MG
MGD-28 is a potent, orally active, Cereblon (CRBN)-dependent IKAROS protein degrader that degrades IKZF1 (DC50=3.8 nM), IKZF2 (DC50=56.3 nM), and IKZF3 (DC50=7.1 nM) in a dose-dependent manner. In addition, MGD-4 also degrades CK1α (DC50=7.8 nM). MGD-28 has antiproliferative activity and can be used in multiple myeloma research.
- Potent
- Orally active
- Cereblon (CRBN)-dependent IKAROS protein degrader
- Degrades IKZF1, IKZF2, and IKZF3 in a dose-dependent manner
- Degrades CK1α
- Antiproliferative activity
- Can be used in multiple myeloma research
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