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Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 50 MG
SDP

Supplier:  Medchemexpress LLC HYB0188A50MG

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Mianserin hydrochloride (Org GB 94) is an orally active H1 receptor antagonist known for activating κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation. This compound modulates social and exploratory behavior, raises electroconvulsive thresholds, and is utilized in research for neurological conditions like depression and epilepsy.

  • Acts as an H1 receptor antagonist
  • Activates κ-opioid receptor and octopamine receptor
  • Increases ERK1/2 and CREB phosphorylation
  • Modulates social and exploratory behavior
  • Raises electroconvulsive thresholds
  • Used in research for neurological diseases
  • Exhibits high affinity for human κ-opioid receptors
  • Inhibits cyclic AMP accumulation mediated by histamine H1

Catalog No. 50-004-07390


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