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Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 50 MG

Supplier: Medchemexpress LLC HYB0188A50MG
Mianserin hydrochloride (Org GB 94) is an orally active H1 receptor antagonist known for activating κ-opioid and octopamine receptors. It increases ERK1/2 and CREB phosphorylation and antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation. This compound modulates social and exploratory behavior, raises electroconvulsive thresholds, and is utilized in research for neurological conditions like depression and epilepsy.
- Acts as an H1 receptor antagonist
- Activates κ-opioid receptor and octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Used in research for neurological diseases
- Exhibits high affinity for human κ-opioid receptors
- Inhibits cyclic AMP accumulation mediated by histamine H1
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