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Apexbio Technology LLC Miconazole 22916-47-8 1g
Supplier: Apexbio Technology LLC B19771000
Miconazole (22916-47-8) is a small-molecule inhibitor targeting fungal cytochrome P450-dependent lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity Miconazole exerts its biological activity primarily through selective binding and inhibition of lanosterol 14 -demethylase an enzyme essential for ergosterol formation In in vitro studies Miconazole demonstrates antifungal activity with reported IC50 values generally ranging from approximately 0 1 to 10 M depending on the fungal species and assay conditions Based on these pharmacological properties Miconazole holds research potential in studying fungal infections fungal lipid metabolism and membrane regulatory pathways as well as in exploring antibacterial applications related to cell membrane-associated metabolic targets
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