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Apexbio Technology LLC Miconazole Nitrate 22832-87-7 1g
Supplier: Apexbio Technology LLC B19781000
Miconazole Nitrate (CAS 22832-87-7) is a small-molecule inhibitor targeting lanosterol 14-alpha-demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and function Miconazole Nitrate exerts its biological activity primarily through inhibition of the enzyme lanosterol 14-alpha-demethylase In in vitro studies Miconazole Nitrate demonstrates antifungal inhibitory activity with IC50 values ranging from approximately 0 1 to 10 M depending on specific fungal species and assay conditions Based on these pharmacological properties Miconazole Nitrate holds research potential in evaluating susceptibility profiles and resistance phenotypes of fungal and bacterial pathogens exploring pathogen-host interactions antimicrobial mechanisms of action and fungal metabolic pathways
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