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Apexbio Technology LLC Milrinone 78415-72-2 100mg
SDP

Supplier:  Apexbio Technology LLC B1386100

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Milrinone (CAS 78415-72-2) is a selective inhibitor of phosphodiesterase 3 (PDE3) demonstrating an IC50 of 56 12 nM for PDE3 inhibition It acts on both PDE3A localized predominantly in cardiac tissue vascular smooth muscle and platelets and PDE3B found in adipose tissue liver and pancreatic islets Milrinone increases intracellular cAMP levels in platelets with an EC50 of 5329 970 nM leading to enhanced contractility and vasodilation effects This profile supports its utility in cardiovascular research and metabolic studies involving cAMP-mediated signaling pathways

Catalog No. 50-000-88708


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