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Selleck Chemical LLC MIRA-1 E4634-5MG

Supplier: Selleck Chemical LLC E46345MG
MIRA-1(NSC 19630) a maleimide compound is a selective inhibitor of Werner syndrome WRN helicase activity with an IC50 of 20 M while sparing ATPase and exonuclease activities It reactivates mutant p53 inducing apoptosis in various human solid tumor cell lines with tetracycline-regulated mutant p53
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