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Medchemexpress LLC Mitiglinide calcium | 145525-41-3 | 98.8% | 334.44 | 250 MG

Supplier: Medchemexpress LLC 250MGHY17398
Mitiglinide calcium, an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. It is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel) and can be used for the research of type 2 diabetes.
- Inhibits Kir6.2/SUR1 channel currents in a dose-dependent manner (IC50 value, 100 nM) in COS-1 cells.
- Suppresses the increase in plasma glucose levels after a meal load and the area under the curve for plasma glucose levels (AUCglucose).
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