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TARGETMOL CHEMICALS INC MIVEBRESIB 10MG

Supplier: TARGETMOL CHEMICALS INC T3712

Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mivebresib (ABBV-075) also known as ABBV-075 is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration the bromodomain inhibitor ABBV-075 binds to the acetyl-lysine binding site in the BRD of certain BRD-containing protein(s) thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling prevents the expression of certain growth-promoting genes and leads to an inhibition of cell growth in susceptible tumors. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins. purity: 98%
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