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Medchemexpress LLC ML-00253764 hydrochloride | 1706524-94-8 | 99.29% | 413.71 | 10 MM * 1 ML
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Supplier:  Medchemexpress LLC HY11012310MM/1ML

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ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a Ki and IC50 of 0.16 μM and 0.103 μM, respectively. It can cross the blood-brain barrier.

  • Acts as a melanocortin receptor 4 (MC4R) antagonist.
  • Crosses the blood-brain barrier.
  • Decreases cAMP production in MC4R-expressing HEK293 cell membranes.
  • Demonstrates in vivo protection against tumor-induced body weight loss in mouse models.
  • Off-white to light yellow solid appearance.

Catalog No. 50-003-44059


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