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Medchemexpress LLC ML-7 hydrochloride | 110448-33-4 | C15H18ClIN2O2S | 5 MG
Supplier: Medchemexpress LLC HY154175MG
ML-7 hydrochloride is a naphthalene sulphonamide derivative that potently inhibits Myosin Light Chain Kinase (MLCK) with an IC50 of 300 nM. It also acts as an inhibitor of YAP/TAZ. In vitro studies indicate its ability to inhibit rabbit portal vein α1-adrenoceptor NSCC and attenuate Dexmedetomidine (DMT)-induced contraction. In vivo, ML-7 hydrochloride has been shown to reduce brain edema formation after traumatic brain injury in mice.
- Inhibits Myosin Light Chain Kinase (MLCK)
- Acts as an inhibitor of YAP/TAZ
- Inhibits rabbit portal vein α1-adrenoceptor NSCC
- Attenuates Dexmedetomidine (DMT)-induced contraction
- Reduces brain edema formation after traumatic brain injury in mice
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