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Medchemexpress LLC ML289 | 1382481-79-9 | 98.3% | 349.42 | 100 MG
Supplier: Medchemexpress LLC HY19630100MG
ML289 (VU0463597) is a potent, selective, and CNS-penetrant mGlu3 (IC50=0.66 μM) negative allosteric modulator. It demonstrates >15-fold selectivity over mGlu2 and is inactive against mGlu5. It is also identified as a click chemistry reagent because it contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This product is for research use only and not sold to patients.
- Potent, selective, and CNS-penetrant mGlu3 negative allosteric modulator
- Displays over 15-fold selectivity over mGlu2
- Inactive against mGlu5
- Click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
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