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Medchemexpress LLC Mln120b | 783348-36-7 | C19H15ClN4O2 | 50 MG
Supplier: Medchemexpress LLC HY1547350MG
MLN120B is a potent, ATP competitive, and orally active inhibitor of IKKβ with an IC50 of 60 nM. It inhibits multiple myeloma cell growth both in vitro and in vivo, and can also be used for research on rheumatoid arthritis.
- Potent, ATP competitive, and orally active IKKβ inhibitor.
- Inhibits multiple myeloma cell growth in vitro and in vivo.
- Suitable for rheumatoid arthritis research.
- High purity (99.76%).
- Appears as an off-white to light yellow solid.
- Soluble in DMSO (≥ 31 mg/mL).
- Inhibits phosphorylation and degradation of IκB.
- Blocks phosphorylation of p65 NF-κB.
- Reduces shuIL-6R, a tumor growth marker.
- Protects against arthritis-induced weight loss.
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