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Medchemexpress LLC MO-I-1100 | 1585217-40-8 | 99.8% | 379.81 | 25 MG
Supplier: Medchemexpress LLC 25MGHY164410
MO-I-1100 is an inhibitor of ASPH (Aspartyl-(Asparaginyl)-β-hydroxylase) enzymatic activity. It suppresses HCC cell migration, invasion, and anchorage independent growth. MO-I-1100 also shows antitumor effects by inhibiting the Notch signaling cascade in HCC.
- MO-I-1100 is an inhibitor of ASPH enzymatic activity.
- It suppresses HCC cell migration, invasion, and anchorage independent growth.
- MO-I-1100 shows antitumor effects by inhibiting the Notch signaling cascade in HCC.
- It inhibits the viability of FOCUS cells, which have high ASPH expression.
- MO-I-1100 reduces tumor growth in an intrahepatic orthotopic xenograft model of HCC.
- It reduces activated Notch 1 and downstream HES1 and HEY1 gene expression in vivo.
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