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Cayman Chemical MogrosIde IIIE 10mg
Supplier: Cayman Chemical 3928610 MG
A cucurbitane glycoside with anti-inflammatory activity; inhibits LPS-induced secretion of IL-1β, IL-6, and TNF-α from, as well as LPS-induced increases in TLR4 levels in, RAW 264.7 macrophages at 50 µM; reduces increases in BALF levels of IL-1β, IL-6, and TNF-α, and increases in lung tissue Mpo activity in a mouse model of LPS-induced acute lung injury at 20 mg/kg; decreases lung fibrosis and inflammation, as well as increases animal survival and reduced lung levels of MMP-9, in a mouse model of bleomycin-induced pulmonary fibrosis at 20 mg/kg per day
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