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Medchemexpress LLC Monocrotaline | 315-22-0 | 325.36 | 1 ML
SDP

Supplier:  Medchemexpress LLC HYN075010MM/1ML

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Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. It demonstrates inhibitory effects on OCT-1 and OCT-2 with IC50 values of 36.8 μM and 1.8 mM, respectively. This compound exhibits antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is also utilized to induce pulmonary hypertension models in rodents.

  • An 11-membered macrocyclic pyrrolizidine alkaloid.
  • Inhibits OCT-1 (IC50: 36.8 μM) and OCT-2 (IC50: 1.8 mM).
  • Possesses antitumor activity and is cytotoxic to hepatocellular carcinoma cells.
  • Used to induce a model of pulmonary hypertension in rodents.
  • Available with a purity of 99.96%.

Catalog No. 50-004-15368


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