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BioVendor, LLC Monomeric Crp Human Elisa BioVendor LLC
Supplier: BioVendor, LLC RBL010R
C-reactive protein (CRP) is a multipotent protein that undergoes conformational changes between circulating native pentameric CRP (pCRP), pentameric symmetrical forms (pCRP*) and monomeric CRP (mCRP) forms. mCRP exhibits strong pro-inflammatory activity and activates platelets, leukocytes, and endothelial cells. Abundant deposition of mCRP in inflamed tissues plays a role in several disease conditions, such as ischemia/reperfusion injury, Alzheimer¿s disease, and cardiovascular disease. Conversion of pCRP to mCRP induces inflammatory signalling, monoacyl phosphatidylcholine generated by PLA2, or by oxidation lipid acyl chains, promotes binding and dissociation of pCRP to mCRP. One kit (96 wells). Type: sandwich ELISA. Sample type: serum, plasma. Sample req: 50 ¿l/well. Cal range: 1.25-80ng/ml. LoD: 0.63ng/ml. Other names: mCRP, monomeric C-reactive protein.
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