Apexbio Technology LLC Montelukast Sodium 151767-02-1 10mM (in 1mL DMSO)

Supplier:  Apexbio Technology LLC B17925.1

Montelukast Sodium (CAS 151767-02-1) is a selective reversible antagonist targeting the leukotriene D4 (LTD4) receptor It inhibits LTD4 receptor binding with Ki values of 0 52 nM in U937 cells 0 18 nM in guinea pig lung and 4 nM in sheep lung In U937 and THP-1 cell membranes Montelukast Sodium has IC50 values of 10 mM and 40 mM respectively against leukotrienes C3 and B4 In animal studies oral administration inhibits LTD4-induced bronchoconstriction with an ED50 of 0 03 mg/kg in conscious squirrel monkeys It is widely utilized in biomedical research investigating leukotriene-mediated inflammatory pathways and respiratory disorders

Catalog No. 50-000-63720