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ACROBiosystems Mouse DM-1 200ug
Supplier: ACROBiosystems DM1PLY73200UG
Mertansine (DM-1) is a tubulin inhibitor that binds to the ends of microtubules and inhibits microtubule dynamics. DM-1(Mertansine) has antitumor activity and functions as a regulator of tubulin. It is an alpha-amino acid ester a carbamate an epoxide an organic heterocyclic tetracyclic compound an organochlorine compound a mercaptan and a maydenin alkaloid. DM-1 derived from Mydenin is a cytotoxic component of antibody-drug conjugations that produce antibody-drug conjugations via a sulfhydryl group splice with SPP (n-succinimide 4- (2-pyridyl dithio)) or SMCC (4- (3-mercapto-2 5-dioxy-1 pyrrolidyl) -cyclohexanic acid) splice.
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