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Medchemexpress LLC MPEP | 96206-92-7 | 99.4% | 193.24 | 100 MG
Supplier: Medchemexpress LLC HY14609A100MG
MPEP is a potent, selective, noncompetitive, orally active, and systemically active mGlu5 receptor antagonist. It completely inhibits quisqualate-stimulated phosphoinositide (PI) hydrolysis with an IC50 of 36 nM. MPEP exhibits anxiolytic- and antidepressant-like effects. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Potent, selective mGlu5 receptor antagonist
- Exhibits anxiolytic-like effects
- Shows antidepressant-like effects
- Functions as a click chemistry reagent
- No agonist or antagonist activity on human mGlu2, -3, -4a, -7b, -8a, and mGlu6 receptors
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