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Medchemexpress LLC MRX-2843 (UNC2371) | 1429882-07-4 | MFCD28502224 | 99.6% | 488.67 g/mol | C29H40N6O | 25 MG
Supplier: Medchemexpress LLC HY10154925MG
MRX-2843 (UNC2371) is an orally active, ATP-competitive small-molecule inhibitor of the MERTK and FLT3 receptor tyrosine kinases used in preclinical research to study signaling, overcome resistance-conferring FLT3 mutations, and evaluate anti-leukemia effects. Analytical data and handling recommendations are provided for laboratory use.
- Potent dual MERTK and FLT3 enzymatic inhibition (IC50 1.3 nM and 0.64 nM).
- Demonstrated activity in cell proliferation assays (Kasumi-1 IC50 ≈ 143.5 nM).
- High purity suitable for research use (99.6% by HPLC).
- Orally active small molecule compatible with in vivo studies.
- Supplied as solid and solution formulations for flexible handling.
- Recommended storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
- Molecular weight 488.67 g/mol; chemical formula C29H40N6O.
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