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Medchemexpress LLC MS4078 anaplastic lymphoma kinase (ALK) PROTAC degrader | 2229036-62-6 | 99.7% | 914.47 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY112155100MG

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MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC degrader based on a Cereblon ligand, demonstrating a Kd of 19 nM for binding affinity to ALK. This product is intended for research use only and is not suitable for patient use.

  • Anaplastic lymphoma kinase (ALK) PROTAC degrader
  • Based on Cereblon ligand
  • 19 nM Kd for binding affinity to ALK
  • Inhibits proliferation of SU-DHL-1 cells with an IC50 of 33 nM
  • Reduces NPM-ALK protein levels in SU-DHL-1 cells
  • Reduces EML4-ALK protein levels in NCI-H2228 cells

Catalog No. 50-004-36802


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