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Medchemexpress LLC MS4322 (isomer) | 2601727-80-2 | 99.9% | C55H76N10O12S | 1 MG
Supplier: Medchemexpress LLC HY141877B1MG
MS4322 (YS43-22) isomer is an isomer of MS4322. It is a specific PRMT5 PROTAC degrader. It can be used for the research of breast cancer, lung cancer, and hepatocellular cancer.
- Reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells.
- Inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM.
- Promotes ubiquitination and degradation of PRMT5.
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