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Medchemexpress LLC MTR-106 | 1639357-93-9 | 99.4% | 525.62 | 5 MG
Supplier: Medchemexpress LLC HY1489535MG
MTR-106 is a potent and orally active G-quadruplex stabilizer and RNA polymerase I inhibitor. It induces apoptosis and inhibits cell growth, making it suitable for cancer research.
- Potent and orally active G-quadruplex stabilizer
- RNA polymerase I inhibitor
- Induces apoptosis and inhibits cell growth
- Has antitumor activity in both HR-deficient cells and PARPi-resistant cells
- Induces cell cycle arrest and DNA damage
- Suppresses tumor growth in BRCA-deficient and PARPi-resistant xenografts in nude mice
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