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Medchemexpress LLC MY-875 | C21H25NO6 | 100 MG
Supplier: Medchemexpress LLC HY150761100MG
MY-875 is a competitive inhibitor of microtubulin polymerization with an IC50 value of 0.92 μM. It functions by targeting colchicine binding sites and activates the Hippo pathway, leading to apoptosis and anticancer activity against various cancer cell lines.
- Competitive inhibitor of microtubulin polymerization
- Targets colchicine binding sites
- Activates the Hippo pathway
- Induces apoptosis and anticancer activity
- Exhibits anti-proliferative activity against various cancer cells
- Inhibits microtubule protein polymerization and β-tubulin alkylation
- Induces phosphorylation of MST and LATS, leading to YAP degradation
- Inhibits cell colony-forming ability and arrests cells in the G2/M phase
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