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Apexbio Technology LLC MYCMI-6 681282-09-7 50mg
Supplier: Apexbio Technology LLC BA276650
MYCMI-6 (CAS 681282-09-7) is a selective inhibitor of endogenous protein-protein interactions specifically targeting the basic helix loop helix leucine zipper (bHLHZip) domain of MYC with a binding affinity of 1 6 M By disrupting interactions at this domain MYCMI-6 blocks MYC-driven transcriptional activity The compound inhibits the proliferation of tumor cells in a MYC-dependent manner with IC50 values below 0 5 M while displaying no cytotoxicity toward normal human cells MYCMI-6 also induces apoptosis in treated cells It is utilized in research settings to investigate MYC function and the consequences of MYC inhibition in cancer biology
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