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Cayman Chemical MyelopRoxIdase InhIbItr Scr
Supplier: Cayman Chemical 700170192 WELL
A state-dependent sodium channel inhibitor selectively binds to inactivated Nav channels over resting Nav channels (Kis 0.6 and 15 UM respectively) inhibits INa in primary rat acutely dissociated hippocampal neurons at 1 UM inhibits early- and late-phase nociceptive responses in the formalin test in mice (ED50s 10.6 and 5.2 mg/kg respectively) reduces the number of MES-induced tonic seizures in mice and rats
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