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Cayman Chemical MyrIstoyl GlycIn 10mg
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Supplier:  Cayman Chemical 3010710 MG

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An a-AR agonist binds to a1A- a1B- a1D- a2A- a2B- and a2C-ARs in a radioligand binding assay (IC50s 0 08 0 56 0 45 0 98 1 8 and 0 22 M respectively) increases intracellular calcium levels in HEK293 cells transfected with human a2B-ARs (EC50 99 M) but not other a-ARs a 5-HT1 receptor agonist (Kis 0 7 and 14 nM for the human 5-HT1D and 5-HT1B receptors respectively) inhibits forskolin-induced cAMP production in CHO Pro 5 cells expressing human 5-HT1D and 5-HT1B receptors by 62 and 49 respectively at 1 M induces contraction of isolated dog nasal mucosal blood vessels at 0 25 g/ml reduces nasal patency in dogs when administered topically or intravenously

Catalog No. 50-299-2542


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