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Medchemexpress LLC MZP-54 | 2010159-47-2 | 98.0% | 1036.67 | 10 MG
Supplier: Medchemexpress LLC HY11237610MG
MZP-54 is a PROTAC connected by ligands for von Hippel-Lindau and BRD3/4, exhibiting a Kd of 4 nM for Brd4BD2. This selective degrader is based on PROTAC technology, binding to VHL-EloC-EloB protein (VCB) with a Kd of 105 ± 24 nM. It shows inhibitory activity against MV4;11 and HL60 cells, and exhibits high depletion of cMyc levels.
- Selective degrader of BRD3/4
- Based on PROTAC technology
- Binds to VHL-EloC-EloB protein (VCB)
- Shows inhibitory activity against MV4;11 and HL60 cells
- Exhibits high depletion of cMyc levels
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