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Medchemexpress LLC N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)propanamide | 1005342-46-0 | MFCD23160049 | >99.0% | 500.6 g/mol | C26H33FN4O3S | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1551810MG

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LCL161 is a small-molecule SMAC mimetic that antagonizes inhibitor-of-apoptosis proteins (IAPs). It is used in preclinical research to promote apoptosis and to sensitize cancer cells to cytotoxic therapies, showing potent activity at nanomolar concentrations.

  • Potent IAP antagonist with nanomolar activity
  • Inhibits XIAP in HEK293 cells (IC50 35 nM)
  • Inhibits cIAP1 in MDA-MB-231 cells (IC50 0.4 nM)
  • Acts as a SMAC mimetic to promote caspase activation
  • Used to study apoptosis, cell death pathways, and combination therapy effects
  • Molecular formula C26H33FN4O3S
  • Molecular weight 500.6 g/mol

Catalog No. 50-002-85871


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