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Medchemexpress LLC N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-6-quinolinecarboxamide | 1609389-52-7 | 99.6% | 429.54 g/mol | C24H23N5OS | 1 ML
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Supplier:  Medchemexpress LLC HY10400810MM 1ML

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ACY-957 is an orally active, selective small-molecule inhibitor of histone deacetylases HDAC1 and HDAC2 used in preclinical research to modulate epigenetic regulation and induce fetal hemoglobin expression. Reported IC50 values are 7 nM (HDAC1), 18 nM (HDAC2), and 1,300 nM (HDAC3). Supplied for in vitro and in vivo studies.

  • Selective inhibition of HDAC1 and HDAC2 with low-nanomolar potency.
  • Demonstrated activity in cellular models of globin gene induction.
  • Orally active in preclinical pharmacology studies.
  • Suitable for both in vitro and in vivo research applications.
  • Characterized with vendor-provided purity and analytical data.

Catalog No. 50-002-44271


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