Medchemexpress LLC N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-6-quinolinecarboxamide | 1609389-52-7 | 99.6% | 429.54 g/mol | C24H23N5OS | 100 MG

Supplier:  Medchemexpress LLC HY104008100MG

ACY-957 is a small-molecule, orally active inhibitor selective for histone deacetylases HDAC1 and HDAC2, used in preclinical research to modulate epigenetic regulation and induce γ-globin expression. CAS 1609389-52-7; formula C24H23N5OS; molecular weight 429.54 g/mol.

• Selective inhibition of HDAC1 and HDAC2 (IC50 7 nM and 18 nM)
• Markedly reduced activity against HDAC3 (IC50 ≈ 1,300 nM), supporting class I selectivity
• Orally active in preclinical models, suitable for in vivo dosing studies
• High reported purity for research-grade material (~99.6%)
• Solid, light yellow to yellow form; stable when stored at -20 °C
• Used to study epigenetic regulation and hemoglobin induction in preclinical research

Catalog No. 50-002-43882