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Medchemexpress LLC N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide | 899713-86-1 | MFCD05123530 | 99.0% | 415.79 g/mol | C18H17ClF3N3O3 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY10073625MG

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ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of acyl-protein thioesterase 1 (APT1/LYPLA1) used as a research tool to probe depalmitoylation and lipid signaling pathways. It is supplied as a solid with documented solubility and storage conditions for in vitro and in vivo studies.

  • Selective and reversible APT1 (LYPLA1) inhibitor (IC50 ≈ 210 nM).
  • Minimal activity against LYPLA2, enabling target-specific studies.
  • Soluble in DMSO (25 mg/mL) for in vitro use; in vivo formulation ≥ 2.5 mg/mL in 10% DMSO/90% corn oil.
  • Powder stability: -20 °C for up to 3 years; in solvent stability: -80 °C recommended.
  • Molecular weight 415.79 g/mol and chemical formula C18H17ClF3N3O3 for experimental calculations.

Catalog No. 50-002-11922


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