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Medchemexpress LLC N-(3,4-difluorophenyl)-1,3,5-trimethyl-4-(2-oxo-2-(prop-2-yn-1-ylamino)acetyl)-1H-pyrrole | 2133017-36-2 | 98.4% | 373.35 | C19H17F2N3O3 | 50MG
SDP

Supplier:  Medchemexpress LLC HY12461450MG

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GLP-26 is a hepatitis B virus (HBV) capsid assembly modulator for antiviral research. It inhibits HBV DNA replication in Hep AD38 cells (IC50 = 3 nM) and reduces covalently closed circular DNA (cccDNA) by >90% at 1 μM. The compound disrupts encapsidation of pre-genomic RNA, can induce nucleocapsid disassembly, and contains an alkyne group compatible with copper-catalyzed azide-alkyne cycloaddition (click chemistry).

  • Potent HBV inhibition with low-nanomolar activity.
  • Reduces cccDNA levels in cell-based assays.
  • Contains an alkyne handle for click-chemistry applications.
  • Available as a solid powder with defined storage stability.
  • High solubility in DMSO for stock solution preparation.

Catalog No. 50-002-37032


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