Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000221146

Medchemexpress LLC N-(3-chloro-4-methylphenyl)-3-(3-((1-(2,6-dioxopiperidin-3-yl)-2,5-dioxo-2,5-dihydro-1H- | 2438124-79-7 | 98.6% | 494.93 g/mol | C25H23ClN4O5 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1457765MG

Encompass_Preferred

ALV1 is a small-molecule molecular glue degrader that induces proteasomal degradation of Ikaros (IKZF1) and Helios (IKZF2) via binding to cereblon (CRBN). It is supplied as a high-purity solid for research use.

  • Potent degrader of Ikaros and Helios (DC50 2.5 nM and 10.3 nM, respectively).
  • Binds cereblon with IC50 of 0.55 μM.
  • High purity solid, light yellow to green-yellow appearance.
  • Soluble in DMSO (50 mg/mL); in vivo formulation examples available.
  • Stable when stored as powder at -20°C (3 years) or 4°C (2 years).

Catalog No. 50-002-21146


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.