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Medchemexpress LLC N-(4-(3-cyano-1-((3,5-dimethylisoxazol-4-yl)methyl)-indol-5-yl)oxyphenyl)pyrrolidine-2-carboxamide | 1704741-11-6 | ≥98.0% | 455.51 g/mol | C26H25N5O3 | 1 ML

Supplier: Medchemexpress LLC HY10197210MM 1ML
AZ-PFKFB3-67 is a potent, selective small-molecule inhibitor of PFKFB3 used for biochemical and cellular research. It inhibits PFKFB3 with an IC50 of 11 nM and shows reduced activity against PFKFB2 and PFKFB1 (159 nM and 1130 nM). The compound is available as a powder and as standard DMSO solutions (1, 5, 10 mM); molecular formula C26H25N5O3 and molecular weight 455.51 g/mol. Store powder at -20°C; store solutions at -80°C or -20°C.
- Potent PFKFB3 inhibition with IC50 = 11 nM.
- Selective over related isoforms (PFKFB2 and PFKFB1).
- Available as powder and DMSO solutions at common concentrations.
- Molecular formula C26H25N5O3; molecular weight 455.51 g/mol.
- Recommended storage: powder -20°C; solutions -80°C or -20°C.
- Suitable for biochemical and cellular assays.
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