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Medchemexpress LLC N-(4-benzyl-3-methyl-1,2,4-thiadiazol-5-ylidene)-N'-phenylbenzenecarboximidamide | 324579-65-9 | 99.9% | 384.50 g/mol | C23H20N4S | 5MG
SDP

Supplier:  Medchemexpress LLC HY1239675MG

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RNF5 inhibitor inh-02 is a small-molecule inhibitor of the E3 ubiquitin ligase RNF5 used for research applications, including studies of F508del-CFTR rescue and autophagy modulation. It has been characterized in cellular models for its ability to restore F508del-CFTR function and to alter autophagic markers.

  • Potent RNF5 inhibition with cell-based EC50 ≈ 2.2-2.6 μM.
  • Rescues F508del-CFTR function in multiple cell models.
  • Modulates autophagy by increasing LC3IIB expression and autophagic vacuole number.
  • Molecular formula C23H20N4S and molecular weight 384.50 g/mol.
  • Reported purity 99.91% and supplied in solid and solution formats for research use.

Catalog No. 50-002-36783


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